Molecular and cytogenetic analysis of infertile Hakka men with azoospermia and severe oligozoospermia in southern China
نویسندگان
چکیده
منابع مشابه
Chromosomal studies in infertile men with oligozoospermia & non-obstructive azoospermia.
BACKGROUND & OBJECTIVE Chromosomal anomalies have been postulated to be as one of the principal genetic factors in male infertility. Cytogenetic evaluation of men with severely compromised semen parameters reveals an increased incidence of chromosomal aberrations when compared with the normal population. The objective of this study was to determine the chromosomal constitution and sperm charact...
متن کاملY Chromosome Microdeletions in Infertile Men with Non-obstructive Azoospermia and Severe Oligozoospermia
BACKGROUND The purpose of the study was to investigate the frequencies and types of Y chromosome microdeletions in infertile men and to analyze the relationship between the levels of reproductive hormones and Y microdeletions. METHODS A total of 1,226 infertile men were screened for Y chromosome microdeletions using multiplex PCR assay. Karyotype analysis was performed on peripheral blood lym...
متن کاملGenetic risk factors in infertile men with severe oligozoospermia and azoospermia.
BACKGROUND Male infertility due to severe oligozoospermia and azoospermia has been associated with a number of genetic risk factors. METHODS In this study 150 men from couples requesting ICSI were investigated for genetic abnormalities, such as constitutive chromosome abnormalities, microdeletions of the Y chromosome (AZF region) and mutations in the cystic fibrosis transmembrane conductance ...
متن کاملFrequency of Y Chromosome Microdeletions Among Iranian Infertile Men with Azoospermia and Severe Oligozoospermia: A Meta-analysis
BACKGROUND While multiple factors can contribute to male infertility, genetic factors, such as chromosomal disorders or Y-chromosome microdeletion, are responsible for about 10% of male infertility. Considering the role of Y-chromosome micro-deletions in men with oligozoospermia who volunteer for in vitro fertilization (IVF), the prevalence of such microdeletions in each particular community ne...
متن کاملfrequency of y chromosome microdeletions among iranian infertile men with azoospermia and severe oligozoospermia: a meta-analysis
background: while multiple factors can contribute to male infertility, genetic factors, such as chromosomal disorders or y-chromosome microdeletion, are responsible for about 10% of male infertility. considering the role of y-chromosome microdeletions in men with oligozoospermia who volunteer for in vitro fertilization (ivf), the prevalence of such microdeletions in each particular community ne...
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ژورنال
عنوان ژورنال: Journal of International Medical Research
سال: 2019
ISSN: 0300-0605,1473-2300
DOI: 10.1177/0300060518816253